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Condensation polymerisation: monomers and repeating units

Organic chemistrySynthetic and natural polymers

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What functional groups react to form an ester link?

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A carboxylic acid group (–COOH) reacts with an alcohol group (–OH) to form an ester link (–COO–) and water.

Key concepts

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Definition and core principle

Condensation polymerisation is a step-growth process in which two functional groups react to form a new covalent bond and a small molecule is lost. The reaction occurs between monomers that each contain at least two reactive functional groups, allowing chain extension in both directions. Each bond-formation step produces a repeating unit and releases a small molecule such as water or HCl, so mass balance excludes the small molecule from the polymer repeating unit.

Functional groups and bond types

Carboxylic acid (–COOH) and alcohol (–OH) react to form an ester (–COO–) plus water, so diacid + diol monomers produce a polyester with ester linkages. Carboxylic acid (–COOH) and amine (–NH2) react to form an amide (–CONH–) plus water, so dicarboxylic acid + diamine monomers produce a polyamide with amide linkages. Amino acids contain both amine and carboxyl groups and polymerise to form polypeptides with amide (peptide) bonds and water elimination.

Repeating units and how they form

Each condensation step removes atoms that become the small molecule, so the repeating unit is the original monomer fragments joined by the new bond with the lost atoms omitted. For a polyester from HO–R–OH and HOOC–R'–COOH, the repeating unit is –[O–R–O–CO–R'–CO]–, shown in simplified form as –[R–O–CO–R']–. For a polyamide from H2N–R–NH2 and HOOC–R'–COOH, the repeating unit is –[R–NH–CO–R']–. The repeating unit indicates the functional groups that previously reacted.

Small molecule elimination and equilibrium

Polymer formation proceeds by many successive condensation reactions that are reversible in principle. Removal of the small molecule (for example by heating, reduced pressure, or use of a dehydrating agent) shifts the equilibrium toward polymer formation and higher molecular mass. Incomplete removal of the small molecule limits chain length and produces oligomers rather than high-molecular-mass polymer.

Examples: polyesters, polyamides and peptides

Polyethylene terephthalate (PET) forms from ethane-1,2-diol (a diol) and benzene-1,4-dicarboxylic acid (a dicarboxylic acid) with ester linkages and water elimination. Nylon-6,6 forms from hexane-1,6-diamine and hexanedioic acid with amide linkages and water elimination. Polypeptides form from amino acids by amide (peptide) bond formation and water elimination. Each example follows the same functional-group pairing principle and produces characteristic repeating units.

Practical factors affecting polymer formation

Temperature, catalysts, stoichiometry and removal of the small molecule control polymer molecular mass and reaction rate. Exact stoichiometric balance of the two monomers maximises chain length because any excess of one monomer terminates growth at that end. Catalysts or acid/heat accelerate bond formation but do not change the type of bond formed, which depends on the reacting functional groups.

Key notes

Important points to keep in mind

Condensation polymerisation requires monomers with at least two reactive functional groups.

Ester links form from carboxyl + alcohol; amide links form from carboxyl + amine.

The repeating unit excludes the small molecule removed during each step.

Removal of the small molecule drives the equilibrium toward polymer formation.

Exact stoichiometric balance of monomers increases average chain length.

Catalysts speed the reaction but do not change bond identity.

Incomplete removal of the small molecule produces oligomers, not high-mass polymer.

Amino acids polymerise by forming peptide (amide) bonds with water elimination.

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